Tuesday, December 22, 2020

2020 Recap & Merry Xmas

2020 was a year of challenges, to say the least Covid-19 brought immense challenges to everyone in 2020, and it brought us our greatest challenge ever: adapting our Spinnaker platform to manage the world’s most complex clinical trial – a trial that tackled Covid-19 head-on.

A recap of REMAP-CAP: the clinical trial fighting Covid-19

As we speak the REMAP-CAP trial has over 3,500 patients enrolled, in over 15 countries, at 300 sites around the world. And during the year, our software randomised over 5,200 patients – go you awesome researchers! I want to take a moment to reflect on the real human impact. It’s easy to get caught up in technical details and statistics, but at the bottom line, the goal of the REMAP-CAP trial, and the Spinnaker platform, is to try and help real people who are sick – in some cases very sick – have a higher probability of receiving a treatment that will help. We feel proud to have been a part of a study with real-world, immediate impact.

REMAP-CAP milestones 

By February, we were already in the thick of adapting our Spinnaker platform to tackle Covid-19. It’s strange to look back to this article in Stuff in March about our work and read that we had just 50 Covid-19 patients enrolled in the clinical trial to investigate the best treatments. By April, our sprint out of the blocks had become a long-distance run, and we settled in for a marathon effort. Even now, in December, as we prepare data for analysis that will hopefully answer questions about COVID-19 treatment in critically ill patients, the finish line seems far away. But this year hasn’t all been about REMAP-CAP! Here’s a look at some of the other studies we’re excited to be a part of.

Updates on studies using Spinnaker »

News about the Spiral team – we’re growing, fast

An increased demand for our services has resulted in a doubling of the team at Spiral, and we’re so happy to have the new hands on deck for what looks like a busy year ahead. During the year, new team members Jess, Emma and Stew all worked on delivering our Spinnaker trial platform along with Cain, Craig and Anna. Jess also delivered... a new baby! The team at Spiral are distributed across New Zealand, and everyone was able to work from home during our lockdown. The only significant effect of the New Zealand lockdowns was to give us more hours in which to work! But it’s not all work for the team and in August, with travel restrictions lifted, we were able to meet up in Wellington for a few days of eating, working and having fun together.

Community Support

We are grateful for the organisations the help make our communities better places and we showed our appreciation by supporting:
  • Innovative Young Minds. A nation-wide programme encouraging young women in STEMM careers.
  • Books in Homes, Xmas Parcels and Reading Assistance in local schools
  • Wikipedia Foundation.
  • Wellington Free Ambulance.

Take care and enjoy this time with your friends and loved ones. Nga kirihimete, god Jul, Merry Christmas, from Audrey and all the team at Spiral

Friday, September 11, 2020

Meet Jess and Emma our Project Managers


Two smart, focussed project managers have joined Spiral recently. It’s very nice to have extra hands on deck to help deliver our Covid-19 projects.

Meet Jess and Emma our Project Managers for REMAP-CAP and for ASCOT-ADAPT.  You can read more about them over on our blog »

Thursday, February 20, 2020

Coronavirus and how we play the adaptation game

We are busy adapting one of our biggest projects to collect data and eventually provide feedback on the best treatment for the novel coronavirus outbreak COVID-19.
Coronavirus mutated( or adapted) recently to give us SARS-CoV-2 and the COVID-19 disease. Adaptation is a great skill for a virus – it's a pretty keen skill for people too, and we are using it to fight back against this disease ... read how »

Tuesday, February 11, 2020

The largest ever cardiac arrest trial performed in an ICU setting uses Spinnaker in novel ways!

January 2020 saw the last patient enrolled in the TTM2 Trial. Congratulations TTM2 – the largest ever cardiac arrest trial performed in an ICU setting!
The trial has been using our Spinnaker Platform in a novel way, which is what this post is about!

Back in 2017 we were approached by Principle Investigator, Niklas Nielsen, looking for a way to streamline the collection of data for TTM2 and a similar study, TAME.  The 2 studies had very similar data points to collect and there seemed to be an opportunity to save time by collecting data just once and sharing it across both studies. Very quickly it got more complicated than that. Patients could be randomised to TTM2, or TAME, or to participate in both studies. The big question was – could the Spinnaker Platform be adapted to this novel design?

We are very proud of our adaptability so we had a close look at what we could do ... follow the story on our blog »